H. Lee Moffitt Cancer Center & Research Institute

September/October 1999

Vol 6, No 5 CME Pretest

In this issue, selected new paradigms in anticancer drugs are persented. First, answer the pretest questions below. After reading the articles, proceed with answering the CME posttest questions.

This Journal provides 4 hours of Category 1 Continuing Medical Education

Complimentary CME Credits

Physicians can earn 4 credit hours of Category 1 for the Physician's Recognition Award of the American Medical Association by reading the material in this issue and successfully answering the questions in the posttest at the end of this issue. Complete instructions are given on the posttest pages. Successfully answering 30 or more questions will earn 4 credit hours. CME is presented by an unrestricted educational grant from Bristol-Myers Squibb Oncology Division.

Educational Objectives

After reading this issue of Cancer Control, clinicians will be expected to:

  • understand signal transduction,
  • be aware of the roles of angiogenesis and angiogenesis inhibitors in cancer,
  • recognize changes in pharmacology that are age-dependent,
  • appreciate the significance of palliative end-points in clinical trials, and
  • know the risk of infection in transfused red blood cells.

This program was planned in accordance with ACCME Essentials.

Release Date: September 1, 1999
Expiration Date: September 1, 2000


Pretest


1. Malignant progression of multiple myeloma is dependent on which signaling pathway?
a. epidermal growth factor (EGF)
b. interleukin 6 (IL-6)
c. transforming growth factor a (TGF-alpha)
d. interferon a (IFN-alpha)

2. What type of chemotherapy-induced nausea and vomiting is particularly problematic in the elderly?

a. anticipatory
b.acute
c.delayed
d.other

3. In a study of palliative endpoints in patients with advanced prostate cancer reported by Tannock et al, the primary indicator of palliation was:
a. time on study
b. fatigue relief
c. pain relief
d.survival



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